Anti-CRK (3H7) Mouse Monoclonal Antibody
Catalog No.
MA2036
Anti-CRK (3H7) Mouse Monoclonal Antibody
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The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
1398
Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; CRK; CRKII; Proto-oncogene c-Crk
Mouse
Human
Unconjugated
Calculated MW: 34 kDa; Observed MW: 34 kDa
Unmodified
IgG2b
Monoclonal Antibody
AP-15C5H3
Liquid
See label
Carrier Not Free
Purified recombinant human CrkII protein fragments expressed in E.coli.
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.