Anti-CD80/CD86 Antibody (Abatacept)
Catalog No.
F2112
Anti-CD80/CD86 Antibody (Abatacept)
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Abatacept is a recombinant protein fused with human immunoglobulin IgG1 and the extracellular domain of CTLA-4. It inhibits T cell co-stimulatory signals, thereby reducing T cell activation, and is mainly used to treat rheumatoid arthritis and juvenile idiopathic arthritis. Abatacept binds to CD80/CD86 molecules on antigen-presenting cells, blocking their interaction with CD28 molecules on T cells, thereby inhibiting T cell activation.
Dry ice
332348-12-6
-80°C
2 years
Liquid
1 mg/mL
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.
CHO
CTLA4lg, BMS-188667, Orencia
100 mM Pro 20 mM Arg pH 5.0.
Human
Unconjugated
Monoclonal
Protein A
IgG1
ELISA, FACS, Kinetics, Functional assay, Animal Model
CD80/CD86
Please avoid freeze-thaw cycles.