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Anti-CD52 Antibody (Alemtuzumab)

Catalog No.
F1073
Anti-CD52 Antibody (Alemtuzumab)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52 that does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen, inducing profound lymphocyte depletion and then restoring T and B cells with a regulatory phenotype. Alemtuzumab is able to produce complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induce apoptosis. Alemtuzumab has the potential to be used in the study of B-cell chronic lymphocytic leukemia.

Quality Control

Quality Control & DataSheet

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M.Wt

146.06 kDa

Shipping

Dry ice

Cas No.

216503-57-0

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

Campath, MabCampath, Lemtrada

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P31358

Reactivity

Human, Mouse, Rat

Conjugation

Unconjugated

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Target

CD52

Note

Please avoid freeze-thaw cycles.