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Anti-CD47 Antibody (Magrolimab)

Catalog No.
F1222
Anti-CD47 Antibody (Magrolimab)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Magrolimab (Hu5F9-G4) is a humanized anti-CD47 antibody. Magrolimab blocks the "don't eat me" signal of CD47, thereby promoting macrophage-mediated phagocytosis. Magrolimab has antitumor activity in malignant bone tumors and breast cancer.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

145.74 kDa

Shipping

Dry ice

Cas No.

2169232-81-7

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

Hu5F9-G4

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

Q08722

Reactivity

Human, Mouse

Conjugation

Unconjugated

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG4

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

Magrolimab inhibited the tumor growth of Raji on NOD.SCID mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 90.0% at 5 mpk at D32.

Target

CD47

Note

Please avoid freeze-thaw cycles.