Anti-CD45 (8C1) Mouse Monoclonal Antibody
Catalog No.
MA1776
Anti-CD45 (8C1) Mouse Monoclonal Antibody
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Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
19264
GP180; L CA; CD45 antigen
Mouse
Human
Unconjugated
Calculated MW: 145 kDa; Observed MW: 145 kDa
Unmodified
IgG1
Monoclonal Antibody
AP-16A2E12
Liquid
See label
Carrier Not Free
Synthetic Peptide of CD45
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, IHC-F, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.