Anti-CD123 & CD3 Antibody (Flotetuzumab)
Catalog No.
F1389
Anti-CD123 & CD3 Antibody (Flotetuzumab)
Featured Products
Flotetuzumab (MGD006; S80880) is a bispecific CD123/CD3 dual affinity retargeting (DART) antibody. Flotetuzumab reactivates T cells by simultaneously binding to CD123 on target cells and CD3 on effector T cells, resulting in T cell-mediated cytotoxicity of target cells. Flotetuzumab has inhibitory efficacy against acute myeloid leukemia (AML) patient-derived xenograft (PDX) models in mice.
Quality Control & DataSheet
- View current batch:
-
Purity > 95% by SDS-PAGE and SEC-HPLC analyses.
- MSDS (Material Safety Data Sheet)
- Datasheet
117.82 kDa
Dry ice
1664355-28-5
-80°C
2 years
Liquid
See label
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.
CHO
MGD006, S80880, RES234
100 mM Pro 20 mM Arg pH 5.0. No preservative!
P26951 & P07766
Human
Unconjugated
Monoclonal
Protein A
scFv
ELISA, FACS, Kinetics, Functional assay, Animal Model
CD123 & CD3
Please avoid freeze-thaw cycles.