Anti-Caspase 11 Rabbit Monoclonal Antibody
Catalog No.
MA1614
Anti-Caspase 11 Rabbit Monoclonal Antibody
Featured Products
Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators.
12363
Caspl; ich-3; CASP-4; Casp11; CASP-11
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 43 kDa; Observed MW: 43,38,25 kDa
Unmodified
IgG
Monoclonal Antibody
AP-1B9D3
Liquid
See label
Carrier Not Free
Recombinant protein of mouse Caspase-11
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.