Anti-BUBR1 Rabbit Monoclonal Antibody
Catalog No.
MA1528
Anti-BUBR1 Rabbit Monoclonal Antibody
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Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.
701
BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1
Rabbit
Human, Hamster
Unconjugated
Calculated MW: 120 kDa; Observed MW: 120 kDa
Unmodified
IgG
Monoclonal Antibody
AP-1C5G2
Liquid
See label
Carrier Not Free
A synthetic peptide of human BubR1
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-P, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.