Anti-Bcl6 Rabbit Monoclonal Antibody
Catalog No.
MA1437
Anti-Bcl6 Rabbit Monoclonal Antibody
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Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NFκB expression, thereby inhibiting NFκB-mediated cellular functions.HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs).
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BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51
Rabbit
Human
Unconjugated
Calculated MW: 79 kDa; Observed MW: 79 kDa
Unmodified
IgG
Monoclonal Antibody
AP-19C4D9
Liquid
See label
Carrier Free
A synthesized peptide derived from human Bcl6
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.