Anti-Bax Rabbit Monoclonal Antibody
Catalog No.
MA1416
Anti-Bax Rabbit Monoclonal Antibody
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Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
581
Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 21 kDa; Observed MW: 21 kDa
Unmodified
IgG
Monoclonal Antibody
AP-13D1H1
Liquid
See label
Carrier Not Free
A synthetic peptide of human Bax
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.