Anti-Bak Rabbit Monoclonal Antibody
Catalog No.
MA1402
Anti-Bak Rabbit Monoclonal Antibody
Featured Products
Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death.
578
BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
Rabbit
Human
Unconjugated
Calculated MW: 23 kDa; Observed MW: 23 kDa
Unmodified
IgG
Monoclonal Antibody
AP-8B11C4
Liquid
See label
Carrier Not Free
A synthetic peptide of human Bak
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-P, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.