Anti-ATG4A Rabbit Monoclonal Antibody
Catalog No.
MA1342
Anti-ATG4A Rabbit Monoclonal Antibody
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The cysteine protease Atg4 is pivotal to autophagosome membrane generation and regulation. Atg4 primes the Atg8 homologue for lipidation by cleaving its carboxy terminus and exposing its glycine residue for E1-like enzyme Atg7. The Atg8 homologue is transferred to the E2-like enzyme Atg3 before forming the Atg8-PE conjugate. During later stages of autophagy, Atg4 can reverse this lipidation event by cleaving PE, thereby recycling the Atg8 homologue.
115201
ATG4A; APG4A; AUTL2; Cysteine protease ATG4A; AUT-like 2 cysteine endopeptidase; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; hAPG4A
Rabbit
Human
Unconjugated
Calculated MW: 45 kDa; Observed MW: 45 kDa
Unmodified
IgG
Monoclonal Antibody
AP-2D11F8
Liquid
See label
Carrier Not Free
A synthetic peptide of human ATG4A
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-P, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.