Anti-APC Rabbit Monoclonal Antibody
Catalog No.
MA1257
Anti-APC Rabbit Monoclonal Antibody
Featured Products
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
324
APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 312 kDa; Observed MW: 160 kDa
Unmodified
IgG
Monoclonal Antibody
AP-12H7E7
Liquid
See label
Carrier Free
A synthesized peptide derived from human APC
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.