Anti-alpha 1 Fetoprotein Rabbit Monoclonal Antibody
Catalog No.
MA1154
Anti-alpha 1 Fetoprotein Rabbit Monoclonal Antibody
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Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .
174
Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
Rabbit
Human
Unconjugated
Calculated MW: 69 kDa; Observed MW: 69 kDa
Unmodified
IgG
Monoclonal Antibody
AP-20D11G5
Liquid
See label
Carrier Free
A synthesized peptide derived from human AFP
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.