Cantuzumab is a monoclonal antibody designed to target and bind to specific antigens on the surface of cancer cells. It belongs to a class of therapeutics called antibody-drug conjugates (ADCs), which combine the targeting capabilities of monoclonal antibodies with the cancer-killing ability of cytotoxic drugs. Cantuzumab specifically targets the CanAg antigen, which is often overexpressed in certain types of cancer, such as colorectal cancer, pancreatic cancer, and certain types of lung cancer. By binding to this antigen, Cantuzumab can deliver its cytotoxic payload directly to cancer cells, thereby minimizing damage to healthy cells and increasing the effectiveness of treatment.
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.
Host
CHO
Alternative Names
huC242, huC242-DM4
Buffer System
100 mM Pro 20 mM Arg pH 5.0.
Reactivity
Human
Conjugation
Unconjugated
Clonality
Monoclonal
Purification
Protein A
Isotype
IgG1
Application
ELISA, FACS, Kinetics, Functional assay, Animal Model