Anti-ABCG2 Rabbit Monoclonal Antibody
Catalog No.
MA1040
Anti-ABCG2 Rabbit Monoclonal Antibody
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ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
9429
ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD338
Rabbit
Human
Unconjugated
Calculated MW: 72 kDa; Observed MW: 72 kDa
Unmodified
IgG
Monoclonal Antibody
AP-10B12G5
Liquid
See label
Carrier Not Free
A synthetic peptide of human BCRP/ABCG2
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.