Anti-5T4 Rabbit Monoclonal Antibody
Catalog No.
MA1023
Anti-5T4 Rabbit Monoclonal Antibody
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5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.
7162
5T4; 5T4AG; M6P1; TPBG; 5T4 oncofetal antigen; Trophoblast glycoprotein
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 46 kDa; Observed MW: 78 kDa
Unmodified
IgG
Monoclonal Antibody
AP-9B4E9
Liquid
See label
Carrier Not Free
A synthetic peptide of human 5T4
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.