Animal Tissue Optical Clearing Kit

Animal Tissue Optical Clearing Kit is a highly effective kit that enables simple, convenient, and rapid high-quality and high-transparency clearing of whole animal bodies, whole organs, tissue blocks, or organoids. Animal samples cleared with this kit can be combined with subsequent immunofluorescence, immunohistochemistry, routine or fluorescent staining, bioluminescence, and other techniques to achieve three-dimensional imaging of tissue blocks, organoids, organs, or even entire animal bodies, making it widely applicable in biomedical research.

CUBIC (Clear, unobstructed brain/body imaging cocktails and computational analysis) is a simple and effective method for animal tissue clearing. The Animal Tissue Optical Clearing Kit achieves clearing effects essentially comparable to conventional CUBIC methods.

The Solution I provided in this kit not only promotes delipidation of tissues and organs but also decolorizes heme in tissues and organs. Solution II adjusts the refractive index of tissues to match that of the solvent, minimizing light scattering within the tissue and facilitating optical imaging.