Amiodarone

Amiodarone (Amiodarone, CAS No.: 1951-25-3) is a drug widely used for the treatment of arrhythmias, mainly exerting its effects by inhibiting ATP-sensitive potassium channels, with an IC₅₀ of approximately 19.1 μM. In biomedical research, amiodarone is often used to establish animal models to study the mechanisms of diseases such as pulmonary fibrosis and potential therapeutic approaches. In in vitro experiments, the activity level of amiodarone is typically in the low micromolar range, with the specific concentration depending on the experimental design and research purpose. In cell and animal models, amiodarone can be applied in various ways, and the selection of dose and concentration is usually based on the specific experimental design and research objectives.