[Ala107]-MBP (104-118)
Catalog No.
B5218
Non-competitive inhibitor of PKC
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[Ala107]-MBP (104-118) is a non-competitive inhibitor of PKC and synthetic peptide analog of bovine myelin basic protein (MBP) with IC50 value of 46 - 145 mM.
References:
1. Substrate specificity of phospholipid/Ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. Turner et al. J.Biol.Chem., 1985;260:11503
2. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Su et al. Biochem.Biophys.Res.Commun., 1986;134:78
| Physical Appearance | White lyophilised solid |
| Storage | Desiccate at -20°C |
| M.Wt | 1493.68 |
| Cas No. | 99026-77-4 |
| Formula | C67H104N20O19 |
| Solubility | Soluble to 1 mg/ml in 10% acetonitrile |
| Chemical Name | (2S,3Z,6Z,8S,9Z,11S,12Z,14S,15Z,17S,18Z,20S,21Z,23S,24Z,26S,27Z,29S,30Z,33Z,35S,36Z,39Z,41S,42Z)-8-((1H-indol-3-yl)methyl)-44-amino-41-(4-aminobutyl)-14-benzyl-17-(3-guanidinopropyl)-4,7,10,13,16,19,22,25,28,31,34,37,40,43-tetradecahydroxy-11,20,26-tris(h |
| SDF | Download SDF |
| Canonical SMILES | CC(C[C@@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/CN)([H])CCCCN)([H])C)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/C/C(O)=N/[C@@](C(O)=O)([H])C)([H])CC1=CNC2=CC=CC=C12)([H])CO) |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
GKGAGLSLSRFSWGA