Abaloparatide acetate
Catalog No.
C8816
A selective PTHR1 agonist that promotes bone formation and improves cortical bone structure.
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Abaloparatide acetate is the acetate form of Abaloparatide (CAS No. 247062-33-5, catalog No. BA5196). Abaloparatide is a selective analogue targeting parathyroid hormone receptor 1 (PTHR1), exerting its effects by activating the Gs/cAMP signaling pathway and enhancing β‑arrestin recruitment. Studies have shown that Abaloparatide promotes bone formation and improves cortical bone structure in animal models. Therefore, this compound is commonly used in studies of bone‑metabolism–related signaling pathways and in exploratory experiments on bone‑metabolic disorders such as osteoporosis.
| Storage | Store at -20°C |
| M.Wt | 3960.6 |
| Cas No. | 247062-33-5 (free base) |
| Formula | C176H304N56O51 |
| Synonyms | BA058 acetate |
| Chemical Name | L-alanyl-L-valyl-L-seryl-L-α-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-α-aspartyl-L-lysylglycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-α-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl- |
| Canonical SMILES | CC(O)=O.C[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC1=CNC=N1)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC(C(C)(C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N) |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
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