6,7-diketolithocholic acid

6, 7-diketocholic acid (6, 7-diketolca) is an important bioactive compound that possesses both anti-inflammatory and bile acid metabolic regulatory activities. As a secondary bile acid with a special structure, it can affect lipid metabolism in the body by acting on bile acid receptors (such as FXR, TGR5, etc.), regulate the balance of glycolipid metabolism, and especially play a role in improving insulin resistance and regulating triglyceride synthesis. Studies have shown that it can intervene in the cholesterol metabolic pathway by inhibiting the activity of key enzymes such as cholesterol 7α -hydroxylase (CYP7A1), and thereby be used to suppress diseases related to abnormal cholesterol metabolism (such as atherosclerosis, non-alcoholic fatty liver disease, etc.). Its biological activity makes it a key molecule connecting the metabolism of intestinal microorganisms with the host's metabolic homeostasis, and it shows potential research value in the intervention of metabolic diseases.