Toggle Nav
Close
  • Menu
  • Setting

5-Ethynyl-2'-deoxyuridine (5-EdU)

Catalog No.
B8337
For fast and sensitive detection of DNA synthesis
Grouped product items
SizePriceStock Qty
100mg
$60.00
In stock
1g
$335.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

5-Ethynyl-2'-deoxyuridine (5-EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferation. 5-EdU can be used as a replacement for BrdU (5-Bromo-2'-deoxyuridine) to measure de novo DNA synthesis during the S-phase of the cell cycle through click chemistry. Click chemistry is a method of covalently coupling an azide with an alkyne. 5-EdU has an alkyne handle that can be detected using azide-containing fluorescent probes through a highly efficient click chemistry reaction. In contrast to the use of BrdU, the new method does not require sample fixation or DNA denaturation. 5-EdU-labelled cells may be isolated to determine the transcript of cells, from neural cancer or tissues that have undergone division in vitro and in vivo.

Product Citation

Chemical Properties

Physical AppearanceSolid
StorageStore at -20°C
M.Wt252.22
Cas No.61135-33-9
FormulaC11H12N2O5
Solubility≥25.2 mg/mL in DMSO; insoluble in EtOH; ≥11.05 mg/mL in H2O with ultrasonic
Chemical Name5-ethynyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
SDFDownload SDF
Canonical SMILESO=C1C(C#C)=CN([C@@H]2O[C@H](CO)[C@@H](O)C2)C(N1)=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control