2-Furoic acid

2-Furoic acid (CAS No.: 88-14-2) is a furan-derived organic compound generated through the oxidation of furfural and is commonly utilized as a biochemical intermediate and research tool in studies of metabolic regulation. It has been reported to exhibit lipid-lowering activity in preclinical models, notably reducing serum cholesterol and triglyceride levels in rat systems, suggesting a modulatory role in lipid metabolism pathways. Although its precise molecular targets remain insufficiently characterized, available evidence indicates that it may influence key processes involved in lipid homeostasis and metabolic signaling. In vitro and in vivo investigations typically employ concentrations spanning the low micromolar range, with dosing parameters varying according to specific experimental designs. Owing to its distinct bioactivity profile, 2-Furoic acid is frequently applied in cell-based assays and animal models to investigate mechanisms of dyslipidemia, screen for metabolic modulators, and explore structure–activity relationships within furan-based compounds in drug discovery research.