2-Chloro-ATP
Catalog No.
B8826
An effective inhibitor of soluble guanylate cyclase
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2-Chloro-ATP, a chlorinated derivative of ATP, is an effective inhibitor of soluble guanylate cyclase, which can specifically inhibit the activity of this enzyme, thus affecting the production of intracellular cGMP. Furthermore, 2-Chloro-ATP works at low concentrations, significantly increasing the intracellular calcium ion (Ca² +) concentration through a mechanism independent of inositol phosphate (IP3) production. This increased concentration of calcium ions may be related to the activation of specific purine receptors (P2 receptors) on the cell membrane.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 541.62 |
| Cas No. | 49564-60-5 |
| Formula | C10H15ClN5O13P3 |
| Solubility | Soluble in DMSO |
| Chemical Name | ((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate |
| SDF | Download SDF |
| Canonical SMILES | ClC1=NC(N([C@@H]2O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)[C@H]2O)C=N3)=C3C(N)=N1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
