2’3’-c-di-AM(PS)2 (Rp,Rp) ammonium salt
Catalog No.
C8600
A potent agonist of interferon gene stimulant (STING)
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2 '3' -c-di-AM(PS)2 (Rp,Rp) ammonium salt (ADU-S100 ammonium salt) is a novel cyclic dinucleotide compound and a potent agonist of interferon gene stimulants (STING). By activating the STING pathway, this compound can effectively induce the production of type I interferons and other pro-inflammatory cytokines, thereby enhancing the immune response of the body. Studies have shown that ADU-S100 ammonium salt has significant anti-tumor activity, effectively promoting the recruitment and activation of immune cells in the tumor microenvironment and inhibiting tumor growth. In addition, it can also enhance the host's immune surveillance function and show good potential for immunotherapy.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 724.60 |
| Cas No. | 1638750-96-5 |
| Formula | C20H30N12O10P2S2 |
| Solubility | Soluble in DMSO |
| Chemical Name | (5R,7R,8R,12aR,14R,15R,15aS,16R)-7,14-bis(6-amino-9H-purin-9-yl)-15,16-dihydroxy-2,10-dimercaptooctahydro-12H-5,8-methanofuro[3,2-l][1,3,6,9,11]pentaoxa[2,10]diphosphacyclotetradecine 2,10-dioxide, diammonia salt |
| SDF | Download SDF |
| Canonical SMILES | NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COP4(S)=O)[C@@H](OP(OC[C@H]5O[C@@H](N6C(N=CN=C7N)=C7N=C6)[C@H](O4)[C@@H]5O)(S)=O)[C@H]3O.N.N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |