11(Z),14(Z)-Eicosadienoic Acid

11(Z),14(Z)-Eicosadienoic Acid (CAS No.: 2091-39-6) is a rare, naturally occurring n-6 polyunsaturated fatty acid predominantly identified in animal tissues and classified within the broader family of long-chain fatty acids involved in lipid metabolism and membrane biology. This molecule is recognized for its incorporation into phospholipid bilayers, where it contributes to the regulation of membrane fluidity and structural organization, and for its role as a metabolic precursor in the biosynthesis of eicosanoid-like lipid mediators that participate in cellular signaling pathways. Mechanistically, it is associated with modulation of lipid signaling networks, including pathways linked to inflammatory responses, enzymatic oxidation processes, and lipid-derived second messengers, although its precise molecular targets remain under active investigation and are often inferred from related polyunsaturated fatty acids. In vitro studies commonly employ this compound to probe lipid metabolism, membrane dynamics, and signal transduction processes, with observed biological effects typically occurring in the low micromolar to micromolar concentration range depending on the experimental system. In vivo and cell-based models utilize this fatty acid to explore its contribution to lipid homeostasis, inflammatory signaling cascades, and metabolic regulation, with dosing and exposure conditions varying according to specific research objectives. As such, 11(Z),14(Z)-Eicosadienoic Acid serves as a valuable research tool in studies of lipid biochemistry, cell physiology, and disease-related metabolic pathways.