1,3-Dilinoleoyl-rac-glycerol

1,3-Dilinoleoyl-rac-glycerol (CAS No.: 15818-46-9) is an unsaturated diacylglycerol characterized by linoleic acid side chains esterified at the sn-1 and sn-3 positions, and is widely utilized as a bioactive lipid intermediate in studies of cellular signaling and lipid metabolism. As a member of the diacylglycerol class, it functions as a lipid second messenger analog capable of modulating pathways associated with protein kinase C activation and other lipid-sensitive signaling cascades, thereby influencing processes such as membrane dynamics, enzyme regulation, and metabolic homeostasis. In vitro studies indicate that compounds of this class can regulate lipid-metabolizing enzymes and signaling proteins with activity typically observed in the nanomolar to micromolar range, although precise potency depends on the experimental system and assay conditions. Owing to its structural and functional relevance, 1,3-Dilinoleoyl-rac-glycerol is commonly employed in biochemical and cell-based models to investigate lipid-mediated signal transduction, enzyme activation, and the role of diacylglycerols in metabolic disorders, including obesity, insulin resistance, and cardiovascular disease. Experimental usage concentrations vary according to specific research objectives, and it is frequently incorporated into lipidomics workflows, enzyme assays, and pharmacological screening platforms targeting lipid-regulated pathways.