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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A1835 Pelitinib (EKB-569)

Summary: EGFR inhibitor,potent and irreversible

insoluble in EtOH; insoluble in H2O; ≥11.7 mg/mL
A2986 ADL5859 HCl

Summary: δ-opioid receptor agonist,selective

≥21.45 mg/mL
A5118 BTZ043 Racemate
2 Citation

Target: DprE

Summary: DprE1 inhibitor

insoluble in H2O; ≥10.4 mg/mL
A2150 Andarine

Target: Androgen Receptors

Summary: Androgen receptor agonist

≥21 mg/mL
A2174 Lenvatinib (E7080)

Target: VEGFR|PDGFR|RET

Summary: VEGFR inhibitor

≥21.35 mg/mL
A1404 Rigosertib sodium salt
1 Citation

Target: PLK

Summary: Plk1 inhibitor

≥23.65 mg/mL
A1186 AMG-208

Summary: C-Met inhibitor,potent and highly selective

insoluble in EtOH; insoluble in H2O; ≥3.83 mg/mL
A1393 WZ8040

Target: EGFR

Summary: EGFR T790M inhibitor,irreversible amd potent

≥24.05 mg/mL
A2806 BX-912

Summary: PDK1 inhibitor,potent and ATP-competitive

≥23.55 mg/mL
A5057 MGCD-265

Target: VEGFR|c-MET

Summary: Met/Flt/Flk/Ron/Tie-2 inhibitor

≥25.9 mg/mL