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TLR

TLR (Toll-like receptor) is a family of receptors that expressed on immune cells including B lymphoctes, macrophages and mast cells. Ir identifies pathogen-associated molecular patterns and mediate the cytokines productions for activation of innate immunity.

  1. Cat.No. Product Name Information
  2. B2133 Suprofen Suprofen is a non-steroidal anti-inflammatory drug (NSAID).
  3. B1187 Imiquimod maleate Imiquimod maleate is an immune response modifier that acts as a toll-like receptor 7 agonist and is commonly used topically to treat warts on the skin of the genital and anal areas.
  4. B1186 Imiquimod hydrochloride Imiquimod hydrochloride is an immune response modifier that acts as a toll-like receptor 7 agonist and is commonly used topically to treat warts on the skin of the genital and anal areas.
  5. B1054 Resiquimod (R-848) Resiquimod (R-848, S-27609) is a modifier of immune response .
  6. A3881 Toll-like receptor modulator Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system.
  7. A3851 TAK-242 S enantiomer S enantiomer of TAK-242. TAK-242 (Resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling. TAK-242 is in treatment of sepsis and septic shock.
  8. A3850 TAK-242

    IC50: With IC50 of 1.1 to 11 nM, TAK-242 inhibited LPS-induced NO production, tumor necrosis factor-alpha and interleukin (IL)-6 in RAW264.7 cells and mouse peritoneal macrophages [1].

  9. B5753 CU CPT 22 New Product
  10. B5752 CU CPT 4a New Product
  11. B5551 Poly(I:C) New Product

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