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Anti-B7-H1/PD-L1/CD274 Antibody (Atezolizumab)

Catalog No.
F1310
Anti-B7-H1/PD-L1/CD274 Antibody (Atezolizumab)
Grouped product items
SizePriceStock Qty
100ug
$54.00
Ship with 3-5 days
1mg
$162.00
Ship with 3-5 days
5mg
$485.00
Ship with 3-5 days
50mg
$1,405.00
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Atezolizumab (CAS 1380723-44-3) is a humanized monoclonal antibody of the IgG1 class targeting programmed death-ligand 1 (PD-L1), also known as B7-H1 or CD274. It functions by selectively binding to PD-L1, thereby preventing interactions between PD-L1 and its receptor PD-1. This blockade helps restore suppressed immune responses, particularly T-cell-mediated tumor surveillance. In biomedical research, atezolizumab serves as a tool in studies investigating immune checkpoint signaling pathways and immunotherapeutic strategies against various cancers.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

145 kDa

Shipping

Dry ice

Cas No.

1380723-44-3

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

RG-7446, RO-5541267

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

Q9NZQ7

Reactivity

Human, Mouse, Cynomolgus

Conjugation

Unconjugated

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

Immobilized human PD-L1 His at 2 ug/mL can bind Anti-B7-H1/PD-L1/CD274 Antibody (Atezolizumab)

Target

B7-H1 / PD-L1 / CD274

Note

Please avoid freeze-thaw cycles.