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PD-1/PD-L1 inhibitor 1

Catalog No.
B6172
PD-1/PD-L1 interaction inhibitor
Grouped product items
SizePriceStock Qty
5mg
$103.00
In stock
25mg
$348.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

PD-1/PD-L1 inhibitor 1 (CAS: 1675201-83-8) is a small molecule inhibitor targeting the interaction between programmed cell death protein 1 (PD-1) and its ligand PD-L1. By disrupting PD-1/PD-L1 signaling, this agent restores and enhances T-cell activation, demonstrating immunomodulatory properties. In vitro assays (HTRF binding assay) report IC50 values ranging from 6 to 100 nM. Current preclinical evidence positions PD-1/PD-L1 inhibitor 1 as a candidate compound for studying tumor immunity and infectious diseases, such as hepatitis C virus infection.

Chemical Properties

StorageStore at -20°C
M.Wt475.58
Cas No.1675201-83-8
FormulaC29H33NO5
Solubilityinsoluble in H2O; insoluble in EtOH; ≥5.98 mg/mL in DMSO with gentle warming and ultrasonic
Chemical Name(S)-1-(2,6-dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid
SDFDownload SDF
Canonical SMILESO=C([C@H]1N(CC2=C(OC)C=C(OCC3=CC=CC(C4=CC=CC=C4)=C3C)C=C2OC)CCCC1)O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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