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EGFR

B6358 Methyl 2,5-dihydroxycinnamate

Summary: EGF receptor-associated tyrosine kinases inhibitor

Soluble in ethanol
B6323 AG 99

Summary: EGFR inhibitor

Soluble in DMSO
B6054 EAI045

Summary: Inhibitor of L858R/T790M EGFR mutants

≥38.3 mg/mL
B5899 CL-387785 (EKI-785)

Summary: Irreversible inhibiter of EGFR

insoluble in EtOH; insoluble in H2O; ≥16.85 mg/mL
B5889 EGF816
2 Citation

Target: EGFR

Summary: Novel covalent inhibitor of mutant-selective EGFR

Soluble in DMSO
B5792 BMS 599626 dihydrochloride

Summary: EGFR and ErbB2 inhibitor,potent and selective

Soluble in DMSO
B5456 HKI 357

Summary: irreversible inhibitor of ErbB2 (HER2) and EGFR

Soluble in DMSO
B1496 Icotinib

Summary: EGFR tyrosine kinase inhibitor

insoluble in H2O; ≥129.6 mg/mL
B1495 OSI-420 free base

Summary: EGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥51 mg/mL
B1105 AZD-9291 mesylate

Summary: third generation EGFRm inhibitor, oral and irreversible

insoluble in EtOH; insoluble in DMSO; insoluble in H2O