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Tyrosine Kinase

B5792 BMS 599626 dihydrochloride

Summary: EGFR and ErbB2 inhibitor,potent and selective

Soluble in DMSO
B5456 HKI 357

Summary: irreversible inhibitor of ErbB2 (HER2) and EGFR

Soluble in DMSO
B5491 (Z)-FeCP-oxindole

Summary: VEGFR-2 inhibitor

insoluble in DMSO
B1496 Icotinib

Summary: EGFR tyrosine kinase inhibitor

insoluble in H2O; ≥129.6 mg/mL
B5490 (E)-FeCP-oxindole

Summary: VEGFR-2 inhibitor

insoluble in DMSO
B1495 OSI-420 free base

Summary: EGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥51 mg/mL
B4657 EG00229

Summary: Nrp1 inhibitor

≥26.25 mg/mL
B2303 Apatinib
4 Citation

Summary: VEGFR2 inhibitor, orally bioavailable, selective

≥49.4 mg/mL
B1105 AZD-9291 mesylate

Summary: third generation EGFRm inhibitor, oral and irreversible

insoluble in EtOH; insoluble in DMSO; insoluble in H2O
B2301 SAR131675

Summary: VEGFR3 inhibitor,selective and ATP-competitve

insoluble in DMSO; insoluble in EtOH; insoluble in H2O