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p53

Items 31-38 of 38

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  1. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  2. Tenovin-1
    A4203 Tenovin-1
    Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21
    Summary: SIRT2 inhibitor, activates p53
      insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
  3. RITA (NSC 652287)
    A4202 RITA (NSC 652287)
    Summary: Mdm2-p53 interaction and p53 ubiquitination blocking
      insoluble in H2O; ≥14.6 mg/mL
  4. RG7388
    A3763 RG7388
     2 Citation
    Summary: MDM2 antagonist, oral, selective
      ≥30.82 mg/mL
  5. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  6. Nutlin-3a chiral
    A3671 Nutlin-3a chiral
     2 Citation
    Summary: MDM2 inhibitor, antiproliferative and antiproapoptotic
      ≥29.07 mg/mL
  7. tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]
    A1094 tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]
    Summary: P53 binding protein fragment
      ≥124.2 mg/mL
  8. p53 tumor suppressor fragment
    A1083 p53 tumor suppressor fragment
    Summary: Regulates cell cycle
      ≥53.3 mg/mL

Items 31-38 of 38

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