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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A4188 2-Methoxyestradiol (2-MeOE2)
2 Citation

Summary: Apoptotic, antiproliferative and antiangiogenic agent

insoluble in H2O; ≥15.25 mg/mL
A4189 IOX2(Glycine)
1 Citation

Summary: HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor

insoluble in EtOH; insoluble in H2O; ≥17.6 mg/mL
A4190 GSK J4 HCl
1 Citation

Summary: Inhibitor of H3K27 demethylase JMJD3,potent and cell-permeable

insoluble in H2O; insoluble in EtOH; ≥13.9 mg/mL
A4191 GSK J1

Summary: H3K27 demethylase JMJD3 inhibitor

≥38.9 mg/mL
A4192 SGI-1776 free base
3 Citation

Summary: Pim kinase inhibitor,ATP-competitive

≥40.5 mg/mL
A4106 Scriptaid
1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,novel and cell-permeable

insoluble in H2O; ≥13.1 mg/mL
A4107 Sodium Phenylbutyrate

Target: Histone Deacetylases (HDACs)

Summary: Histone deacetylase inhibitor

≥27.65 mg/mL
A4108 Resminostat (RAS2410)
1 Citation

Summary: Potent HDAC inhibitor

Soluble in DMSO
A4110 MLN8237 (Alisertib)
10 Citation

Summary: Aurora A Kinase inhibitor, Potent and selective

≥25.95 mg/mL
A4111 VX-680 (MK-0457,Tozasertib)
1 Citation

Target: Aurora Kinases

Summary: Aurora kinase inhibitor

≥23.25 mg/mL