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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A4164 AZD2461

Target: PARP

Summary: Novel PARP inhibitor

insoluble in H2O; ≥16.35 mg/mL
A4168 Entacapone

Target: Catechol O-Methyltransferase (COMT)

Summary: COMT inhibitor
A4171 EPZ005687
2 Citation

Target: EZH2

Summary: EZH2 inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
A4176 Thioguanine

Summary: Purine antimetabolite

insoluble in EtOH; insoluble in H2O; ≥8.35 mg/mL
A4180 SRT1720 HCl
3 Citation

Target: Sir2-like Family Deacetylases (Sirtuins)

Summary: SIRT1 activator

≥25.3 mg/mL
A4181 EX 527 (SEN0014196)
12 Citation

Target: Sirtuin

Summary: SIRT1 inhibitor

insoluble in H2O; ≥12.43 mg/mL
A4182 Resveratrol
2 Citation

Target: Sir2-like Family Deacetylases (Sirtuins)|COX|LOX|Adenylyl cyclase|Quinone reductase

Summary: SIRT1 activator
A4183 Sirtinol

Summary: SIRT inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.7 mg/mL
A4184 PFI-1 (PF-6405761)
1 Citation

Target: Bromodomains

Summary: BET inhibitor

insoluble in H2O; insoluble in EtOH; ≥128.4 mg/mL
A4187 FG-4592 (ASP1517)
5 Citation

Summary: HIF prolyl-hydroxylase inhibitor

insoluble in H2O; ≥17.62 mg/mL