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Bioactive Compounds

Bioactive Compounds

A4117 AT9283

Summary: Aurora kinase/JAK inhibitor

insoluble in H2O; ≥19.05 mg/mL
A4217 QNZ (EVP4593)
6 Citation

Summary: Potent NF-κB inhibitor
A4305 WY-14643 (Pirinixic Acid)
8 Citation

Target: PPAR

Summary: PPARα agonist,selective and highly potent

insoluble in H2O; ≥16.2 mg/mL
A4327 Tadalafil

Target: Phosphodiesterases (PDEs)

Summary: PDE5 inhibitor

insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL
A4394 Docetaxel
9 Citation

Summary: Microtubulin disassembly inhibitor

≥40.4 mg/mL
A3124 5-hydroxypyrazine-2-carboxylic acid

Summary: Metabolite of pyrazinamide (PZA)

insoluble in EtOH; ≥7 mg/mL
A3256 BMS-690514

Summary: HER/EGFR inhibitor

Soluble in DMSO
A3268 CAL-130 Hydrochloride

Summary: PI3K inhibitor

Soluble in DMSO
A3317 Clozapine N-oxide (CNO)
53 Citation

Target: DREADD Ligands

Summary: Metabolite of clozapine

insoluble in EtOH and H2O; ≥17.15 mg/mL
A3336 CVT-313
1 Citation

Target: Cyclin-Dependent Kinases

Summary: Cdk2 inhibitor

≥20 mg/mL