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Bioactive Compounds

Bioactive Compounds

B5859 Entrectinib

Target: Trk Receptors|ALK|ROS1

Summary: Orally active inhibitor of ALK kinase

≥28.05 mg/mL
B5942 AS601245

Summary: c-Jun NH2-terminal protein kinase inhibitor

insoluble in H2O; insoluble in EtOH; ≥14.25 mg/mL
A1044 Gap 26
24 Citation

Target: Gap Junctions

Summary: Gap junction blocker peptide, mapping to connexin 43 residue 63-75

insoluble in EtOH; ≥155.1 mg/mL
A8737 S63845
39 Citation

Target: MCL1

Summary: MCL1 inhibitor
A3001 Ibrutinib
7 Citation

Summary: Bruton's tyrosine kinase (BTK) inhibitor

≥22.02 mg/mL
A4139 AG-490
3 Citation

Target: EGFR|JAK

Summary: JAK2/EGFR inhibitor

insoluble in H2O; ≥14.7 mg/mL
A4144 AZ 960

Target: JAK

Summary: JAKs inhibitor

Soluble in DMSO
A4483 PRIMA-1

Target: p53

Summary: BAX inhibitor

≥110.6 mg/mL
A4528 EB 47

Summary: Potent PARP-1 inhibitor

<30.52 mg/mL
A4452 Mitomycin C
9 Citation

Summary: Inhibits DNA synthesis,antibiotic and antitumor agent

insoluble in H2O; insoluble in EtOH; ≥16.7 mg/mL