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Bioactive Compounds

Bioactive Compounds

A5017 Motesanib Diphosphate (AMG-706)

Summary: VEGFR/ PDGFR/c-Kit/Ret inhibitor

≥28.45 mg/mL
A5176 AS-605240

Target: PI3K

Summary: Potent and selective PI 3-Kγ inhibitor

insoluble in H2O; insoluble in EtOH; ≥4.28 mg/mL
A5323 Moxifloxacin HCl
1 Citation

Target: Antibiotic

Summary: Fluoroquinolone antibiotic

insoluble in EtOH; ≥43.91 mg/mL
A5700 BS-181 HCl

Target: Cyclin-Dependent Kinases

Summary: CDK7 inhibitor,highly selective

insoluble in H2O; ≥20.85 mg/mL
A5803 BIX 02188

Target: MEK

Summary: MEK5 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL
A8317 Fludarabine Phosphate (Fludara)
2 Citation

Target: STAT

Summary: Inhibits STAT1 activation and DNA synthesis

insoluble in EtOH; ≥17.6 mg/mL
A8449 Indomethacin
4 Citation

Target: COX

Summary: Cox inhibitor
A8397 Chlorothiazide

Target: Carbonic Anhydrases

Summary: Carbonic anhydrase inhibitor

insoluble in H2O; insoluble in EtOH; ≥14.85 mg/mL
A8554 Dapivirine (TMC120)

Target: Reverse Transcriptases

Summary: Nonnucleoside reverse transcriptase inhibitor

insoluble in H2O; ≥13.5 mg/mL
A8633 Concanamycin A
9 Citation

Target: Vacuolar-type ATPase

Summary: V-type (vacuolar) H+-ATPase inhibitor

soluble in DMSO