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Bioactive Compounds

Bioactive Compounds

A8405 Cytarabine
1 Citation

Summary: cytotoxic agent, blocks DNA synthesis

insoluble in EtOH; ≥28.6 mg/mL
B3261 RO4987655

Summary: MEK inhibitor

insoluble in H2O; insoluble in EtOH; ≥56.6 mg/mL
B1642 WYE-125132 (WYE-132)

Target: mTOR

Summary: ATP-competitive mTOR inhibitor, highly potent

insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
B2075 Ambrisentan

Target: ETA Receptors

Summary: ETA-receptor antagonist

insoluble in H2O; ≥18.92 mg/mL
B1302 Amsacrine

Summary: Topoisomerase 2 inhibitor

≥26.5 mg/mL
B1054 Resiquimod (R-848)
6 Citation

Target: Toll-like receptors (TLRs)

Summary: Toll-like receptor 7/8 (TLR7/8) dual agonist; for autoimmune disease models
B1253 Tenofovir maleate

Summary: Reverse transcriptase inhibitor

Soluble in DMSO
B3680 Griseofulvin

Summary: Microtubule associated inhibitor

insoluble in EtOH; insoluble in H2O; ≥10.45 mg/mL
B4727 B-Raf IN 1

Summary: B-Raf inhibitor

Soluble in DMSO
B6586 (-)-Lobeline hydrochloride

Summary: nicotinic receptor partial agonist