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Bioactive Compounds

Bioactive Compounds

A2025 Plerixafor (AMD3100)

9 Citation

Summary: CXCR4 chemokine receptor antagonist

≥25.14 mg/mL
A2323 TCS 359

Summary: Potent FLT3 inhibitor

insoluble in EtOH; insoluble in H2O; ≥9 mg/mL
A2521 VE-821

9 Citation

Summary: ATR kinase inhibitor

≥62.5 mg/mL
A2623 VU 0364439

Summary: Positive allosteric mGluR-4 modulator

≥21.11 mg/mL
A1174 AMG-517

Target: TRP Channel

Summary: TRPV1 antagonist,potent and highly selective

≥21.5 mg/mL
A1387 AZD5363

6 Citation

Target: Akt

Summary: AKT inhibitor,pyrrolopyrimidine derived

≥21.45 mg/mL
A1929 Macitentan

Summary: Endothelin (ET)(A) and ET(B) receptor antagonist

≥24.4 mg/mL
A2005 Nutlin-3b

Target: p53-MDM2 interaction

Summary: MDM2/p53 inhibitor
A1769 KU-0060648

1 Citation

Target: PI3K|DNA-PK

Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
A2664 VX-661

2 Citation

Target: CFTR

Summary: F508del CFTR corrector

≥21.8 mg/mL