Afatinib
Catalog No.
A4746
Featured Products
- 1. Irit Shapira-Netanelov, Olga Furman, et al. "Patient-Derived Gastric Cancer Assembloid Model Integrating Matched Tumor Organoids and Stromal Cell Subpopulations." Cancers (Basel). 2025 Jul 9;17(14):2287 PMID: 40723172
- 2. Yuhan Ding, Yao Yan, et al. "NRG1-ErbB4 signaling in the cerebrospinal fluid-contacting nucleus regulates thermal pain in mice." Neuroscience. 2025 Feb 6:566:132-141. PMID: 39733821
| Storage | Store at -20°C |
| M.Wt | 485.94 |
| Cas No. | 850140-72-6 |
| Formula | C24H25ClFN5O3 |
| Synonyms | BIBW 2992 |
| Solubility | ≥49.3 mg/mL in DMSO; ≥13.07 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide |
| SDF | Download SDF |
| Canonical SMILES | CN(C)C/C=C/C(Nc(c(O[C@@H]1COCC1)c1)cc2c1ncnc2Nc(cc1)cc(Cl)c1F)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure








