Signaling Pathways
Items 1951-1960 of 6763
per page
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C5615 MMP-2 Inhibitor ISummary: reversible inhibitor of matrix metalloproteinase (MMP)-2≤50 mg/mL -
C5802 CarazololSummary: high-affinity, lipophilic, non-selective ligand of the β-adrenergic receptorsinsoluble in H2O; ≥14.8 mg/mL -
C5551 FR122047 (hydrate)Summary: selective inhibitor of COX-1≤1 mg/mL -
C5565 F16Summary: potential antitumor agent≤500 μg/mL -
C5813 CFI-400945Summary: orally available, selective inhibitor of polo-like kinase 4 (PLK4)insoluble in H2O; ≥109.8 mg/mL -
C5722 10074-G5Summary: c-Myc inhibitor≥37.9 mg/mL -
C5581 O-Acetyl Salicylhydroxamic AcidSummary: irreversible, non-selective inhibitor of COX-1 and COX-2≤25 mg/mL -
C5739 DL-threo-PPMP (hydrochloride)Summary: inhibitor of glucosylceramide synthase≤10 mg/mL -
C5591 Indomethacin N-octyl amideSummary: potent but non-selective inhibitor of both COX-1 and COX-2≤2 mg/mL -
C5751 24α-methyl CholesterolSummary: agonist at liver X receptors (LXR)insoluble in DMSO; ≥11.68 mg/mL
Items 1951-1960 of 6763
per page
Relate Categories
Category
- Proteases241item
- Apoptosis225item
- Chromatin/Epigenetics372item
- Metabolism444item
- MAPK Signaling152item
- Tyrosine Kinase351item
- DNA Damage/DNA Repair234item
- PI3K/Akt/mTOR Signaling190item
- Microbiology & Virology331item
- Cell Cycle/Checkpoint250item
- Ubiquitination/ Proteasome84item
- JAK/STAT Signaling103item
- TGF-β / Smad Signaling107item
- Angiogenesis60item
- GPCR/G protein1093item
- Stem Cell121item
- Membrane Transporter/Ion Channel660item
- Cancer Biology45item
- Endocrinology and Hormones190item
- Neuroscience763item
- Obesity, Appetite Control & Diabetes7item
- Peptide Inhibitors and Substrate1 item
- Other Signal Transduction47item
- Others849item
- Immunology/Inflammation134item
- Cardiovascular32item
- Vitamin D Related17item
- NF-κB3item
- Autophagy2item
- Metabolic Enzyme/Protease145item
- Alkaloids9item
- Anti-infection75item
- Cell Cycle/DNA Damage13item
- Acids and Aldehydes16item
- Protein Tyrosine Kinase/RTK1 item
- Neuronal Signaling6item
- Terpenoids and Glycosides3item
- Epigenetics1 item
- Immunology2item
- Wnt/β-catenin1 item
- Microbiology2item
- MAPK/ERK1 item
Specificity
Reversibility
Target
- Caspases14item
- Cyclin-Dependent Kinases33item
- Adenosine A2A Receptors5item
- Proteasome14item
- Cathepsins11item
- Histone Deacetylases (HDACs)37item
- Inhibitor of apoptosis proteins (IAP)3item
- Akt13item
- Bcl-29item
- PI3K38item
- CXCR7item
- Raf13item
- Aurora Kinases23item
- Bcl-xl3item
- CSF-1R4item
- Glycoproteins1 item
- p971 item
- Gap Junctions4item
- MDM23item
- EZH26item
- mTOR22item
- Bromodomains8item
- AP-13item
- MMP10item
- Thymidine Phosphorylases1 item
- Androgen Receptors6item
- Peptidylprolyl isomerases1 item
- Acyl coenzyme A: cholesterol acyltransferases1 item
- Myosin II ATPases1 item
- DT-diaphorases1 item
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- MER1 item
- FLT319item
- GSK-311item
- Factor Xa4item
- Farnesoid X receptors (FXRs)3item
- LPA Receptors5item
- P-glycoprotein (P-gp)6item
- PLK11item
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- ULK11 item
- Eph Receptors3item
- VEGFR41item
- PDGFR27item
- c-Kit13item
- RET4item
- IRAK5item
- Bromodomain-containing proteins(BRDs)1 item
- Phosphodiesterases (PDEs)17item
- Mcl-17item
- Hydrolase1 item
- Thymidylate Synthase3item
- p3810item
- PKB1 item
- 3-phosphoglycerate dehydrogenase1 item
- JNK8item
- SGK2item
- Bcr-Abl15item
- Kynurenine-3-monooxygenase1 item
- MEK16item
- PORCN1 item
- DOT1L3item
- FGFR17item
- Nrf23item
- Insulin-like growth factor receptors(IGFRs)1 item
- CGRP receptors2item
- Pim4item
- GABAB Receptors2item
- Liver X receptors (LXRs)4item
- Glucagon-like peptide 1 (GLP-1) receptors2item
- Sir2-like Family Deacetylases (Sirtuins)6item
- Voltage-gated Sodium (NaV) Channels11item
- Deubiquitinating enzymes (DUBs)5item
- PP11 item
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- Ribosomal s6 kinases (RSK)1 item
- Neuraminidases (NA)3item
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- Src19item
- RARs10item
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- BTK2item
- Purinergic (P2Y) Receptors1 item
- RIP kinases1 item
- PAK3item
- PD-1/PD-L1 interaction1 item
- Hypoxia Inducible Factors (HIFs)2item
- Tankyrases1 item
- Inositol Phosphatases1 item
- FAK6item
- BMP and Other Activin Receptors4item
- JAK22item
- p3001 item
- Stearoyl-CoA 9-desaturase (SCD-1)2item
- Syk7item
- Progesterone Receptors4item
- EZH12item
- DNA-PK8item
- HSP9012item
- AMPK5item
- Gutathione S-transferase2item
- CCR2item
- PDHK1 item
- Angiotensin AT2 Receptors2item
- eIF4E/eIF3G interaction1 item
- Notch1 item
- S-nitrosoglutathione reductase1 item
- CFTR4item
- TNKS1 item
- Topoisomerases16item
- Cytochrome P450 (CYP450)14item
- M3 Receptors4item
- thrombin1 item
- Ksp2item
- Ribosomes1 item
- Renin2item
- HIV proteases1 item
- Pepsins1 item
- Influenza viruses1 item
- ErbB5item
- Ferroptosis1 item
- S6 kinases1 item
- Toll-like receptors (TLRs)6item
- Adenosine Kinases2item
- Actin3item
- Serine Proteases2item
- DNA Methyltransferases5item
- Epac1 item
- Calcitonin and Related Receptors1 item
- Survivin1 item
- Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs)1 item
- ERK7item
- HMG-CoA Reductases6item
- Vacuolar-type ATPase1 item
- Kinases1 item
- c-MET8item
- BMI-11 item
- PKC15item
- Calpains5item
- CysLT11 item
- Ubiquitin-specific proteases1 item
- M1 Receptors3item
- HCV Proteases3item
- Ca2 /calmodulin-dependent protein kinases (CaMKs)8item
- MLK31 item
- SMYD21 item
- CREBBP2item
- EP3002item
- Protease-Activated Receptors2item
- Lyn2item
- SGLT2item
- RAD512item
- Trypsins1 item
- HER23item
- Pyk23item
- USP2item
- 5-HT2 Receptors12item
- LRRK26item
- Calcium ionophores1 item
- S1P receptors3item
- Voltage-gated Calcium Channels (CaV)12item
- Calcium chelator1 item
- DGAT2item
- Insulin and Insulin-like Receptors5item
- PARP8item
- Prostaglandin EP receptors1 item
- CB1 Receptors3item
- Melanocortin (MC) Receptors1 item
- Pyruvate dehydrogenases (PDH)2item
- ALK9item
- ROS12item
- Sphingosine kinases (SphKs)3item
- Trypsin1 item
- Chymotrypsin1 item
- Kallikrein1 item
- Trypsinogen1 item
- KRAS G12C1 item
- GTPases1 item
- Monocarboxylate transporters (MCTs)2item
- CETP2item
- NK1 Receptors1 item
- Dehydrogenase2item
- PKG3item
- PKA8item
- Myosin light chain kinases (MLCKs)3item
- GPR302item
- BCPCF efflux1 item
- HIV-1 gp1201 item
- D1 and D5 Receptors5item
- D2 Receptors9item
- D3 Receptors5item
- 5-HT1 Receptors10item
- 5-HT7 Receptors3item
- CaM-KK1 item
- Valosin-containing protein (VCP)1 item
- AdipoR11 item
- AdipoR21 item
- MELK1 item
- Serotonin reuptake1 item
- Insulin-like growth factors (IGFs)1 item
- Pancreatic and duodenal homeobox 1 (PDX1)1 item
- AMPA1 item
- Clk1 item
- TBK11 item
- MARK11 item
- NUAK12item
- Integrin-ligand interactions1 item
- CSF1R1 item
- Bromodomain and Extra-Terminal motif (BET)1 item
- NUAK21 item
- Na /H Exchangers (NHEs)1 item
- Lactate Dehydrogenases (LDH)3item
- MK24item
- Fatty-acid-binding proteins (FABPs)1 item
- 5-HT3 Receptors6item
- Angiotensin-Converting Enzymes (ACEs)4item
- Tie-25item
- RSK3item
- p70 S6K1 item
- Free Fatty Acid Receptors3item
- phosphatases2item
- ROS and Other Gaseous Donors1 item
- Autophagy5item
- ATM/ATR8item
- Acetylcholine1 item
- Mixed lineage kinase domain-like protein (MLKL)1 item
- COX15item
- C5a receptors1 item
- Heparanases1 item
- Folate Analogue1 item
- YAP1 item
- CK12item
- IDH21 item
- Histamine H4 Receptors2item
- Farnesyl Diphosphate Synthases1 item
- CK24item
- HIPK21 item
- HIPK31 item
- HIV Integrases2item
- Cryptochromes1 item
- G-quadruplexes1 item
- Squalene epoxidases4item
- PRAK1 item
- MAPKAP-K21 item
- Delayed rectifier outward potassium current (IKr)1 item
- Melatonin Receptors2item
- 20S proteasomal chymotrypsin1 item
- Geranylgeranyltransferase I1 item
- Farnesyltransferase1 item
- NAT101 item
- Nampt3item
- eIF4F1 item
- Cdc421 item
- SRPK11 item
- P2X Receptors3item
- Glutaminases2item
- Carbonic Anhydrases7item
- Ron1 item
- AP endonucleases1 item
- G9a2item
- BLM1 item
- HSV3item
- Adenosine A2B Receptors1 item
- NADPH Oxidases3item
- Glutamate (Metabotropic) Group I Receptors3item
- Calcium-activated chloride channels (CaCC)1 item
- GPR351 item
- Urokinases2item
- Aldehyde Dehydrogenases2item
- Synthases/Synthetases4item
- MAGL1 item
- NPY Receptors2item
- c-Fyn1 item
- Leukotriene and Related Receptors2item
- TAK11 item
- Histamine H1 Receptors12item
- RAR/RXR2item
- Sigma Receptors2item
- Na /K ATPases2item
- P1101 item
- Hck2item
- Inositol-requiring enzyme 1 (IRE1)1 item
- SETD71 item
- Na /K /Cl- Symporters (NKCCs)2item
- GABAA Receptors3item
- iNOS1 item
- Histamine H2 Receptors1 item
- Phospholipases1 item
- TRP Channel3item
- RNA Polymerases3item
- DYRK1 item
- Norepinephrine transporter1 item
- 5-HT Transporters3item
- Ionophores2item
- Xanthine oxidoreductases1 item
- Dihydroorotate dehydrogenase1 item
- Guanylyl Cyclases1 item
- FoxM11 item
- Histone Demethylases1 item
- Apoptosis Inducers1 item
- M2 Receptors2item
- MNK2item
- 5-Lipoxygenases1 item
- NO Donors / Precursors1 item
- CB2 Receptors2item
- Glucocorticoid Receptors5item
- HIV-1 reverse transcriptase1 item
- IL Receptors2item
- CCL21 item
- Norepinephrine transporters1 item
- 15-lipoxygenases1 item
- Calcium-Activated Potassium (KCa) Channels3item
- 5-HT4 Receptors1 item
- AChE3item
- Insulin Receptors2item
- IRG-1R1 item
- Penicillin-binding proteins (PBPs)1 item
- Proton Pump1 item
- cAMP1 item
- Sulfonylurea receptors1 item
- eEF-21 item
- Inward Rectifier Potassium (Kir) Channels6item
- Arp2/3 complex1 item
- Peptidoglycan synthesis1 item
- CRTH21 item
- Cdc71 item
- calcium chelator1 item
- Nuclear Receptors1 item
- CMV2item
- ZAP-701 item
- Catechol O-Methyltransferase (COMT)2item
- fibrinolysis1 item
- Angiotensin AT1 Receptors4item
- D4 Receptors3item
- O6-methylguanine-DNA-methyl-transferase (MGMT)1 item
- NMDA receptor1 item
- Aldosterone receptor1 item
- HBV Proteases1 item
- M4 Receptors1 item
- M5 Receptors1 item
- Hydroxylases2item
- Flk-11 item
- Adenine receptors1 item
- Antioxidants1 item
- Papains2item
- RNA synthesis1 item
- Protein Arginine Methyltransferases1 item
- IMPDH1 item
- Na /Ca2 Exchangers (NCXs)1 item
- NAE2item
- Ubiquitin-activating Enzyme E12item
- SUMOylation1 item
- ATGL1 item
- BACE3item
- Cytidine deaminases1 item
- GPR401 item
- Adenylyl Cyclases1 item
- angiogenesis1 item
- Glucagon Receptors1 item
- 15-PGDH1 item
- DPP-45item
- DREADD Ligands1 item
- PP41 item
- c-RET3item
- Nonstructural protein 5B (NS5B)1 item
- guanylyl cyclase2item
- ETA Receptors2item
- ETB Receptors1 item
- p70 rsk3item
- voltage-gated chloride channels1 item
- FPTase2item
- AChR8item
- Retinoic acid-related Orphan Receptors (RORs)1 item
- dopamine receptor1 item
- 5-HT1 Receptor3item
- 5-HT2 Receptor2item
- Microtubule/Tubulin3item
- Myosin1 item
- VEGFR3/FLT41 item
- NTRK1/TRKA1 item
- CSF-1R/c-Fms1 item
- interleukin receptor2item
- Menin-MLL2item
- Tryptophan hydroxylases (TPH)2item
- ADAMs1 item
- NMPRTase1 item
- Bfl-11 item
- TAM kinase1 item
- sodium channels1 item
- p53-MDM2 interaction2item
- nuclear export1 item
- CRM11 item
- PTP1 item
- endothelin receptor1 item
- KDR2item
- calcium uptake1 item
- Fyn kinase1 item
- Abl kinases1 item
- PARs1 item
- AXL1 item
- Glyoxalase I1 item
- dCTP Pyrophosphatases1 item
- Protein polybromo-11 item
- SMARCA41 item
- SMARCA21 item
- Dipeptidyl-peptidase II1 item
- p538item
- metalloprotease1 item
- adrenoceptor2item
- HDAC2item
- Antifungal2item
- KDM2item
- 5-HT6 Receptor1 item
- LOX1 item
- Adenylyl cyclase1 item
- Quinone reductase1 item
- 5-HT receptors1 item
- sodium channel3item
- c-Fms tyrosine kinase1 item
- PAR2item
- human lyase1 item
- insulin1 item
- Ub-conjugating enzyme (E2) complex1 item
- Smoothened receptor1 item
- quinone oxidoreductase1 item
- cysteine protease2item
- Nrf2/ARE signal1 item
- PPAR7item
- haspin kinase1 item
- STK1 item
- HDM2 ubiquitin ligase1 item
- USP1/USF1 complex1 item
- IKK1 item
- GABA receptors1 item
- MSK1 item
- prostaglandin FP receptor1 item
- gp120-CD4 interaction1 item
- TRPV1 item
- HCV polymerase3item
- Lyn kinase1 item
- Ftase1 item
- Subtilisin/Kex2p-like proprotein convertase1 item
- PC-PLC2item
- Elastases1 item
- GK1 item
- P97 ATPase1 item
- ATP synthase1 item
- NTPDases1 item
- Vitamin D receptors (VDRs)5item
- Antibiotic6item
- Mer tyrosine kinase1 item
- Hec11 item
- Calmodulins1 item
- cannabinoid receptor1 item
- EAA receptor1 item
- neprilysin1 item
- Calcium-Sensing Receptors (CaSRs)2item
- DNA Alkylating2item
- GLI1 item
- Stem Cell Differentiation1 item
- PP2A/Nkd interaction1 item
- Rev-Erb Receptors1 item
- HMGCR1 item
- AAT1 item
- ErbB-21 item
- adrenergic receptor5item
- HIV1 item
- 5-HT4 Receptor1 item
- PAR receptor1 item
- TRPA1 item
- sterol demethylase1 item
- PDK-11 item
- GAPDH1 item
- telomerase1 item
- Prostanoid Receptors1 item
- Histone Acetyltransferases (HATs)3item
- Telomerases1 item
- Retinoid X receptors (RXR)1 item
- complex I of the mitochondrial electron transport chain1 item
- constitutive androstane receptor (CAR)1 item
- F1 Fo-ATPase1 item
- NPFF receptor1 item
- Prk1 item
- potassium channel1 item
- calcium channel1 item
- Ribonucleotide Reductases1 item
- Trx1 item
- Tyrosinases1 item
- Neurokinin receptor1 item
- HSP701 item
- Pregnane X receptor(PXR)1 item
- ICAM1 item
- ITK1 item
- HIF-PH1 item
- NOD11 item
- NUAK1 item
- Rho1 item
- Aryl hydrocarbon receptors (AHRs)1 item
- Ubiquitin E3 Ligases1 item
- DCLK21 item
- FAAH1 item
- PTK2item
- integrase1 item
- L3MBTL1 item
- phosphatidylinositol kinase1 item
- NOS2item
- MDMX1 item
- TYK22item
- MUSK1 item
- MAP3K1 item
- GPR31 item
- AMPA Receptors1 item
- Lck1 item
- Adenosine Deaminases2item
- mitochondrial pyruvate carrier (MPC)1 item
- DNA gyrase1 item
- sodium chloride cotransporter1 item
- SERT1 item
- Thrombin Receptor1 item
- prolactin secretion1 item
- gonadotropin release1 item
- DprE1 item
- Vitamin D1 item
- carnitine reabsorption1 item
- Histamine receptors1 item
- GluR1 item
- 5-HT receptor2item
- dopamine receptors1 item
- AMPA receptor1 item
- 5-alpha Reductases1 item
- Flk12item
- SAPK1 item
- p211 item
- DNA Ligases1 item
- NOP Receptors1 item
- Prostaglandin synthesis1 item
- Protein Tyrosine Phosphatases1 item
- alkaline phosphatases1 item
- ATPases1 item
- Transferases1 item
- benzodiazepine receptor1 item
- Dopamine receptor1 item
- Histamine receptor1 item
- glutamate release1 item
- PAFR1 item
- Aromatases2item
- DHFR1 item
- GARFT1 item
- 5-HT1 item
- PHF1 item
- FGR1 item
- YES2item
- Fyn2item
- ARG1 item
- Autotaxin1 item
- UCH1 item
- RHA1 item
- HCV NS3-4A protease1 item
- TRPC channel1 item
- PKD1 item
- Octamer-binding transcription factor 4 (Oct4)1 item
- Thioredoxin Reductases1 item
- P2Y Receptors1 item
- enoyl-acyl-carrier protein reductase1 item
- SHIP1 item
- FKBP1 item
- MCL11 item
- Bcl-w1 item
- glutathione peroxidase 41 item
- NADH oxidase1 item
- GLP-2 receptor1 item
- S-adenosylhomocysteine hydrolase1 item
- Rho-kinase1 item
- tropomyosin receptor kinase1 item
- LSD1 item
- DDX31 item
- LPA1 item
- PRMT1 item
- ACE1 item
- GLP1 item
- SK1 item
- MST1 item
- PPK1 item
- c-Syk1 item
- CDK1/CyclinB1 item
- NHE1 item
- IDO1 item
- Tph1 item
- FXR1 item
- Cx431 item
- PIM1 kinase1 item
- phospholipase A21 item
- reverse transcriptase1 item
- GABAA receptor1 item
- epoxide hydrolase1 item
- ghrelin receptor1 item
- Serotonin (5-HT) reuptake1 item
- Cholesterol absorption1 item
- Vascular Disrupting Agents (VDA)1 item
- Androgen Receptor1 item
- Substance P/NK1 Receptor1 item
- gp120/CD41 item
- Histone Methyltransferase1 item
- ATM2item
- Sirtuin1 item
- NE1 item
- CRF1 Receptors1 item
- PIKfyve1 item
- Bax1 item
- Glycogen Phosphorylases1 item
- Somatostatin Receptors1 item
- MTH11 item
- PTEN1 item
- Insulin Receptor1 item
- NS3/4a Proteases1 item
- Ca2 -ATPases1 item
- p90 S6K1 item
Reported Experiments
Related Disease
- Abscesses And Esophageal Candidiasis1 item
- Acne2item
- Acute Disseminated Candidiasis1 item
- Acute Kidney Injury2item
- Acute Lung Injury1 item
- Acute Myelogenous Leukemia6item
- Acute Myeloid Leukemia30item
- Acute Renal Failure1 item
- Adrenocortical Carcinoma4item
- Advanced Renal Cell Carcinoma1 item
- Anesthesia2item
- Autoimmune Diseases1 item
- Bacterial Infectios1 item
- Biliary Cancer1 item
- Bladder Cancer12item
- Bladder Carcinoma4item
- Bladder Diseases2item
- B-lymphoid Malignancies1 item
- Brain Injuries Studies3item
- Breast Cancer140item
- Cancer623item
- Candida Peritonitis1 item
- Candidemia1 item
- Castration-resistant Prostate Cancer1 item
- Cervical Cancer7item
- Cholangiocarcinoma2item
- Chronic Lymphocytic Leukemia8item
- Chronic Myeloproliferative Disorders1 item
- Clear Cell Renal Cell Carcinoma2item
- Cocaine Abuse1 item
- Cocaine-Related Disorders2item
- Colon Cancer50item
- Colon Carcinoma7item
- Colorectal Cancer46item
- Depression2item
- Diabetes14item
- Diffuse Large B-cell Lymphoma1 item
- Dyskinesia1 item
- Dyslipidemia2item
- Epilepsy7item
- Erectile Dysfunction4item
- Friedreich's Ataxia1 item
- Fungal Infection3item
- Fungi1 item
- Glioblastoma36item
- Glioma20item
- HCV5item
- Heart Failure6item
- Hepatic Cancer2item
- Hepatitis C4item
- Hepatocellular Carcinoma8item
- HIV16item
- HIV Infections14item
- Hypercholesterolemia3item
- Immunological Diseases1 item
- Immunosuppressive Therapy1 item
- Inflammation1 item
- Inflammatory Bowel Disease1 item
- Inflammatory Diseases24item
- Influenza3item
- Kidney Injury Studies3item
- Leukemia35item
- Liver Cancer5item
- Lung Cancer50item
- Lung Carcinoma4item
- Lymphoma38item
- Mantle Cell Lymphoma2item
- Medulloblastoma1 item
- Melanoma43item
- Mixed Lineage Leukemia3item
- Multidrug Resistance Studies1 item
- Multiple Myeloma27item
- Myelofibrosis2item
- Myeloma8item
- Narcolepsy1 item
- Neuroblastoma15item
- Neurocognitive Disorders1 item
- Neuronal Protection1 item
- Non-small Cell Lung Cancer29item
- Non-small Cell Lung Carcinoma3item
- Obsessive-Compulsive Disorder1 item
- Osteoporosis4item
- Ovarian Cancer41item
- Pain Relief1 item
- Pancreatic Cancer51item
- Pancreatic Carcinoma3item
- Pentacyclic Triterpenoid1 item
- Prostate Cancer62item
- Psoriasis7item
- Psoriasis Vulgaris1 item
- Pulmonary Arterial Hypertension2item
- Pulmonary Fibrosis2item
- Renal Cancer5item
- Renal Cell Carcinoma11item
- Rheumatoid Arthritis16item
- Sarcoma1 item
- Schizophrenia13item
- Sleep Disorders2item
- Soft Tissue Sarcoma1 item
- Squamous Cell Carcinoma3item
- Testicular Cancer2item
- Thyroid Cancer6item
- Transplantation1 item
- Tuberculosis5item
- Type 2 Diabetes26item