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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A5639 BIRB 796 (Doramapimod)
1 Citation

Summary: P38 MAPK inhibitor,cell permeable and highly selective

≥26.4 mg/mL
A5653 AT7867

Target: Akt|PKA|p70 rsk

Summary: Akt1/2/3 and p70S6K/PKA inhibitor

≥16.9 mg/mL
A5700 BS-181 HCl

Target: Cyclin-Dependent Kinases

Summary: CDK7 inhibitor,highly selective

insoluble in H2O; ≥20.85 mg/mL
A5703 BMS-777607

Target: MET

Summary: C-Met inhibitor, potent and selective

≥25.65 mg/mL
A5707 PD318088

Target: MEK

Summary: Allosteric MEK1/2 inhibitor, non-ATP competitive

≥28.05 mg/mL
A5719 AT7519

Target: Cyclin-Dependent Kinases

Summary: Multi-CDK inhibitor
A5734 Fasudil (HA-1077) HCl
1 Citation

Target: ROCK

Summary: Protein kinase inhibitor

≥16.4 mg/mL
A5755 MK-1775
2 Citation

Summary: Wee1 kinase inhibtor,potent and ATP-competitive

≥25.03 mg/mL
A5760 KRN 633

Summary: VEGFR inhibitor,ATP-competitive

insoluble in EtOH; insoluble in H2O; ≥13.75 mg/mL
A5786 Natamycin
1 Citation

Summary: Antifungal macrolide polyene

insoluble in EtOH; insoluble in H2O; ≥16.43 mg/mL