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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A5455 AEE788 (NVP-AEE788)

Summary: EGFR/HER-2/VEGFR inhibitor

≥22.05 mg/mL
A5459 PHA-793887
1 Citation

Target: Cyclin-Dependent Kinases

Summary: Pan-Cdk inhibitor

insoluble in H2O; ≥18.05 mg/mL
A5478 AZD6482

Target: PI3K

Summary: PI3Kβ inhibitor,potent and selective

insoluble in H2O; ≥20.4 mg/mL
A5489 Zibotentan (ZD4054)
1 Citation

Summary: ETA receptor antagonist,potent and specific

insoluble in EtOH; insoluble in H2O; ≥7.2 mg/mL
A5511 Ofloxacin

Target: Topoisomerases|DNA gyrase

Summary: Fluoroquinolones,antibiotics

insoluble in H2O; insoluble in EtOH; ≥12.03 mg/mL
A5559 Cefaclor

Summary: Cephalosporin antibiotic inhibiting cell wall synthesis.

insoluble in EtOH; insoluble in DMSO; ≥3.68 mg/mL
A5566 LY2228820
1 Citation

Target: p38

Summary: P38 MAP kinase inhibitor

≥30.65 mg/mL
A5573 Pimasertib (AS-703026)

Target: MEK

Summary: MEK1/2 inhibitor

≥21.55 mg/mL
A5618 Daclatasvir (BMS-790052)

Target: HCV Proteases

Summary: HCV NS5A inhibitor

≥36.6 mg/mL
A5634 SAR245409 (XL765)

Summary: mTOR/PI3K inhibitor

insoluble in H2O; insoluble in EtOH; ≥15 mg/mL