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Home >> Signaling Pathways >> Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for  Cell Cycle/Checkpoint

Research Area

  1. Cat.No. Product Name Information
  2. A8717 THZ2 CDK7 inhibitor
  3. A8732 Senexin B CDK8/CDK19 inhibitor, highly potent, selective and orally available
  4. B4787 SF1670 PTEN inhibitor, potent and specific
  5. A3921 Vinorelbine ditartrate Anti-mitotic chemotherapy drug
  6. A3291 CCT241533 Potent Chk2 inhibitor
  7. A3210 AZ20 ATR inhibitor,potent and selective
  8. B1383 VE-822 ATR inhibitor
  9. A8336 KU-60019 Top Seller ATM kinase inhibitor,potent and selective
  10. A4605 KU 55933 Top Seller ATM inhibitor,potent and selective
  11. A8626 ETP-46464 ATR inhibitor,potent and selective
  12. A8625 CP-466722 ATM inhibitor,potent and reversible
  13. A8624 CGK733 ATM/ATR inhibitor,potent and selective
  14. A2521 VE-821 Top Seller ATR kinase inhibitor
  15. B5389 Mirin Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor
  16. A4125 CYC116 Potent Aurora A/B inhibitor
  17. A4127 GSK1070916 Aurora B/C inhibitor
  18. A4128 PF-03814735 Aurora A/B inhibitor
  19. A3214 AZD1152 Aurora B kinase inhibitor,highly potent and selective
  20. A3760 Reversine A3 adenosine receptor antagonist,ARK-1/-2/-3 inhibitor
  21. A3804 SCH-1473759 Aurora A/B inhibitor
  22. A3939 XL228 IGF1R/AURORA /FGFR1-3/ABL/SRC family kinases inhibitor
  23. A4488 Anacardic acid HAT inhibitor
  24. A4489 TC-A 2317 hydrochloride Aurora kinase A inhibitor,potent and selective
  25. A4124 TAK-901 Novel Aurora A/B inhibitor
  26. A4122 PHA-680632 Aurora kinase inhibitor,novel and potent
  27. A4121 SNS-314 Mesylate Aurora A/B/C kinases inhibitor, potent and selective
  28. A4129 ENMD-2076 L-(+)-Tartaric acid Aurora kinases inhibitor
  29. A4113 ZM 447439 Aurora Kinase inhibitor,potent and selective
  30. A4112 Barasertib (AZD1152-HQPA) Top Seller Aurora Kinase B inhibitor, Potent and selective
  31. A4111 VX-680 (MK-0457,Tozasertib) Top Seller Aurora kinase inhibitor
  32. A4130 ENMD-2076 Selective Aurora A/Flt3 inhibitor
  33. A4131 CCT129202 Aurora kinase inhibitor,ATP-competitive and potent
  34. A4132 CCT137690 Aurora A/B/C inhibitor
  35. A4114 MLN8054 Aurora A inhibitor
  36. A4115 JNJ-7706621 Potent CDK/Aurora kinase inhibitor
  37. A4116 Danusertib (PHA-739358) Top Seller Pan-aurora kinase inhibitor
  38. A4120 MK-5108 (VX-689) Aurora-A kinase inhibitor,highly selective
  39. A4119 AMG-900 Aurora kinase inhibitor
  40. A4118 Hesperadin Top Seller Aurora B kinase inhibitor
  41. A4117 AT9283 Aurora kinase/JAK inhibitor
  42. A4110 MLN8237 (Alisertib) Top Seller Aurora A Kinase inhibitor, Potent and selective
  43. A4126 Aurora A Inhibitor I Aurora A inhibitor
  44. A8807 MK-8745 Aurora A inhibitor,potent and selective
  45. A8300 ZCL278 Selective Cdc42 inhibitor
  46. B9014 ML 141 Cdc42 GTPase inhibitor
  47. B6103 Casin GTPase Cdc42 inhibitor
  48. C4738 MLS-573151 Cdc42 inhibitor
  49. B1232 XL413 Cdc7 inhibitor
  50. A3721 PHA-767491 Cdc7/cdk9 inhibitor, potent, ATP-competitive
  51. B1015 XL413 hydrochloride Cdc7 inhibitor
  52. A8638 LY2603618 Chk1 inhibitor,highly selective
  53. B1088 LY2606368 CHK1 inhibitor
  54. B1236 BML-277 Chk2 inhibitor,potent and highly selective
  55. B1437 PF-477736 Chk1 inhibitor
  56. C3012 SB 218078 checkpoint kinase 1 (Chk1) inhibitor
  57. B5880 CCT244747 Potent and selective CHK1 inhibitor
  58. A9908 Chk1 and MK2 Inhibitors set Chk1- and MK2 inhibitors
  59. A3292 CCT241533 hydrochloride CHK2 kinase inhibitor, novel
  60. A5919 AZD7762 Top Seller Checkpoint kinase inhibitor,ATP competitive
  61. A8477 MK-8776 (SCH-900776) Chk1 inhibitor,potent and selective
  62. A8394 CHIR-124 Chk1 inhibitor,novel and potent
  63. B7249 TCS 2312 checkpoint kinase 1 (chk1) inhibitor
  64. B7248 NSC 109555 ditosylate Chk2 inhibitor,ATP-competitive
  65. A1169 10058-F4 C-Myc-Max dimerization inhibitor
  66. C5722 10074-G5 c-Myc inhibitor
  67. C3014 KJ Pyr 9 c-Myc inhibitor, cell-permeable
  68. B1464 KPT-330 CRM1 inhibitor, orally bioavailable and selective
  69. B1462 KPT-185 CRM1 inhibitor,selective and irrversible
  70. B1463 KPT-276 inhibitor of nuclear export (SINE) and CRM1, orally bioavailable
  71. B4889 Verdinexor (KPT-335) XPO1/CRM1 inhibitor
  72. A8882 THZ1 Top Seller Covalent CDK7 inhibitor,potent and selective
  73. A8641 LEE011 CDK4/6 inhibitor
  74. A8412 Dinaciclib (SCH727965) Top Seller Potent CDK inhibitor
  75. A8326 AZD-5438 Top Seller Potent CDK1/2/9 inhibitor
  76. B8002 LY2857785 CDK9 inhibitor
  77. B4830 RGB-286638 CDKs inhibitor
  78. A8885 Ro 3306 An ATP-competitive, potent CDK1 inhibitor
  79. B4990 Purvalanol A potent, and cell-permeable CDK inhibitor
  80. B7633 PF 4800567 hydrochloride casein kinase 1ε inhibitor
  81. B7464 TMCB CK2 and ERK8 inhibitor
  82. B7445 (R)-DRF053 dihydrochloride cdk/CK1 inhibitor,potent and ATP-competitive
  83. B7128 Ryuvidine SETD8 protein lysine methyltransferase (PKMT) inhibitor
  84. B6956 NSC 625987 Cyclin-dependent kinase (cdk) 4 inhibitor
  85. B6935 Aminopurvalanol A cyclin-dependent kinase inhibitor
  86. B6892 NSC 693868 CDKs and GSK-3 inhibitor
  87. B5926 AZD-5597 Potent CDK inhibitor
  88. A8718 GX-674 Nav1.7 antagonist
  89. B7855 Alsterpaullone CDKs and GSK3β inhibitor
  90. C4040 Olomoucine cdk inhibitor
  91. C3767 Iso-Olomoucine inactive stereoisomer of the Cdk5 inhibitor olomoucine
  92. C3679 Cdk1/2 Inhibitor III Cdk1/cyclin B and Cdk2/cyclin A inhibitor
  93. C3995 Cdk4/6 Inhibitor IV Cdk4/cyclin D1 and Cdk6/cyclin D1 inhibitor
  94. B6192 ON123300 multi-targeted kinase inhibitor,inhibits CDK4, Ark5, PDGFRβ, FGFR1, RET, and Fyn
  95. B6101 Bohemine CDK inhibitor
  96. B7798 PD 0332991 (Palbociclib) CDK4/6 inhibitor,highly selective
  97. A8739 CCT251545 analogue, Compound 51 Potent, Selective, orally bioavailable CDK 8/19 Inhibitor
  98. A8736 THZ531 CDK12 and CDK13 covalent inhibitor
  99. B6042 K03861 CDK2 inhibitor
  100. B4831 RGB-286638 free base novel CDK inhibitor
  101. A3197 AT7519 Hydrochloride Multi-CDK inhibitor
  102. A1980 SNS-032 (BMS-387032) Top Seller CDK inhibitor
  103. A3806 SCH900776 S-isomer Checkpoint kinase(Chk)inhibitor
  104. A3794 SB1317 CDK,JAK and FLT inhibitor
  105. A3676 NVP-LCQ195 CDK1/CDK2/CDK5 inhibitor
  106. A3575 LY2835219 free base CDK inhibitor
  107. A3417 Flavopiridol Pan-cdk inhibitor
  108. A3336 CVT-313 Cdk2 inhibitor
  109. A3303 CGP60474 CDKs and PKC inhibitor, potent
  110. A3295 CDK9 inhibitor 2 CDK9 inhibitor
  111. A3294 CDK9 inhibitor CDK9 inhibitor
  112. A3293 CDK inhibitor II CDK inhibitor
  113. A3266 BS-181 CDK7 inhibitor,highly selective
  114. A3198 AT7519 trifluoroacetate CDK/cyclin inhibitor
  115. A1723 Roscovitine (Seliciclib,CYC202) CDK inhibitor,potent and selective
  116. A5459 PHA-793887 Pan-Cdk inhibitor
  117. B1233 CDK4 inhibitor CDK4/Cyclin D1 inhibitor
  118. B6720 Kenpaullone CDK1/cyclin B and GSK-3β inhibitor
  119. B7063 Arcyriaflavin A cdk4/cyclin D1 inhibitor
  120. B5220 [Ala92]-p16 (84-103) inhibitor of cyclin-dependent kinase-4 (cdk4)/cyclin D1
  121. A8640 Flavopiridol hydrochloride CDK inhibitor, potent and selective
  122. A8639 Deferasirox Oral iron chelator
  123. A8565 Purvalanol B CDK1/CDK2/CDK4 inhibitor
  124. A8385 BMS265246 CDK1/2 inhibitor,potent and selective
  125. A5700 BS-181 HCl CDK7 inhibitor,highly selective
  126. A5719 AT7519 Multi-CDK inhibitor
  127. A1794 LY2835219 CDK4/6 inhibitor,potent and selective
  128. A8316 PD 0332991 (Palbociclib) HCl Top Seller CDK4/6 inhibitor,highly selective
  129. A8335 Palbociclib (PD0332991) Isethionate Top Seller CDK4/6 inhibitor,highly selective
  130. A8501 PHA-848125 CDK inhibitor,potent and ATP-competitive
  131. A1986 Nu 6027 ATR/CDK inhibitor, potent and selective
  132. A8642 R547 CDK1/2/4 inhibitor,ATP-competitive
  133. B4754 LDC000067 CDK9 inhibitor, novel and highly specific
  134. B3707 ML167 Clk4 inhibitor,highly selective
  135. B1085 LEE011 succinate hydrate CDK inhibitor
  136. A8643 WHI-P180 EGFR/Janus Kinase 3 inhibitor
  137. B3277 AMG 925 FLT3/CDK4 inhibitor,potent and selective
  138. B1234 WHI-P180 hydrochloride inhibitor of Cdk2, EGFR and Janus Kinase 3
  139. B1083 LEE011 hydrochloride CDK inhibitor
  140. B1084 LEE011 succinate CDK inhibitor
  141. B4736 THZ1 Hydrochloride CDK7 inhibitor
  142. B4665 CDK7-IN-1 potent and selective CDK7 inhibitor
  143. A4467 SU 9516 Cdk2 inhibitor
  144. B1244 PYZD-4409 E1 enzyme inhibitor
  145. A3119 360A G-quadruplex structures inhibitor
  146. A3742 Pyridostatin Drug used for promoting growth arrest
  147. A3120 360A iodide G-quadruplex structures inhibitor
  148. A3309 CHR-6494 Haspin inhibitor,potent ands selective
  149. B8009 UNC0379 N-lysine methyltransferase SETD8 inhibitor
  150. B3280 Kif15-IN-1 potent Kif15 kinesin inhibitor
  151. B3281 Kif15-IN-2 potent Kif15 kinesin inhibitor
  152. C5188 Eg5-I potent inhibitor of Eg5
  153. A3450 GSK-923295 Top Seller CENP-E inhibitor,small-molecule
  154. B6039 ARQ 621 Eg5 inhibitor
  155. B6075 Monastrol Eg5 inhibitor
  156. C5018 Monastrol reversible, cell-permeable inhibitor of the motor protein Eg5
  157. B3706 MPI-0479605 Mps1 inhibitor,selective and ATP competitive
  158. A5343 Ispinesib (SB-715992) Kinesin spindle protein (KSP)inhibitor
  159. A4458 ARRY 520 trifluoroacetate KSP inhibitor
  160. A3188 ARRY-520 R enantiomer KSP inhibitor
  161. B1590 SB743921 Potent KSP inhibitor
  162. B4757 INH6 Hec1/Nek2 inhibitor, potent
  163. B3387 Eribulin synthetic analogue of halichondrin B
  164. B3386 Eribulin mesylate synthetic analogue of halichondrin B
  165. B1634 Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium microtubule destabilizing drug, water-soluble
  166. B1320 Cys-mcMMAD Potent tubulin inhibitor
  167. B2157 Cabazitaxel Microtubule associated inhibitor
  168. A1623 Epothilone A Microtubule stabilizing macrolide
  169. A1630 Epothilone B (EPO906, Patupilone) Microtubule stabilizing macrolide
  170. A1493 ABT-751 (E7010) Inhibitor of microtubule polymerization,antimitotic
  171. A4393 Paclitaxel (Taxol) Top Seller Antineoplastic agent
  172. A4394 Docetaxel Top Seller Microtubulin disassembly inhibitor
  173. A4395 10-DAB (10-Deacetylbaccatin) Top Seller Precursor of antitumor compound Palitaxel and Docetaxel
  174. A3128 7-xylosyltaxol Taxol (Paclitaxel) derivative
  175. A3324 Colchicine Tubulin Inhibitor
  176. A3344 D-64131 Tubulin polymerization inhibitor
  177. A3370 Docetaxel Trihydrate Depolymerisation of microtubules inhibitor
  178. A3394 Epothilone D Natural polyketide compound
  179. A3731 Podophyllotoxin Antineoplastic
  180. A3910 Vc-MMAD Potent tubulin inhibitor
  181. A1765 Vincristine sulfate Microtubule disrupter,antitumor agent
  182. C4226 Phomopsin A cyclic hexapeptide mycotoxin that binds β-tubulin
  183. C4087 Mebendazole broad-spectrum anthelmintic that inhibits intestinal microtubule synthesis
  184. C3889 Ferulenol antimycobacterial activity and stimulates tubulin polymerization
  185. B6076 Myoseverin microtubule-binding molecule
  186. B1066 Dolastatin 10 trifluoroacetate Antitumor agent
  187. B6986 Flutax 1 A fluorescent taxol derivative used for direct imaging of the microtubule cytoskeleton
  188. A3631 Monomethyl auristatin E Antimitotic agent
  189. A3630 MMAD Tubulin inhibitor,highly potent
  190. A3590 Mc-MMAD Potent tubulin inhibitor
  191. B7788 MPC 6827 hydrochloride Potent microtubule inhibitor
  192. B5922 Cevipabulin Anti-microtubule agent
  193. B5870 ELR510444 Novel microtubule disruptor
  194. B4892 TAI-1 Hec1 inhibitor, potent, first-in-class
  195. B1035 Dolastatin 10 Antitumor agent
  196. B3058 CK-636 Arp2/3 complex inhibitor
  197. B3680 Griseofulvin Microtubule associated inhibitor
  198. B3062 CW069 allosteric inhibitor of HSET, selective
  199. B1636 Vinflunine Tartrate Microtubule associated inhibitor
  200. B1635 CYT997 (Lexibulin) Potent microtubule polymerization inhibitor
  201. B3526 Vintafolide folate-targeted chemotherapeutic conjugate

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