N-Ethyl-N-nitrosourea
Catalog No.
C8733
A potent DNA alkylating agent, commonly used to induce and establish animal tumor models.
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N-Ethyl-N-nitrosourea (ENU, CAS 759-73-9) is a potent DNA alkylating agent. It mainly alkylates DNA nucleotides, causing base mismatches and strand breaks, thereby inducing gene mutations. ENU can induce benign and malignant tumors in multiple animal models in tissues including neural tissue, stomach, esophagus, pancreas, respiratory tract, intestine, lymphoreticular tissue, skin, and kidney. In cellular and animal models, ENU is commonly used to induce specific gene mutations for studying gene function and disease mechanisms. In addition, ENU is used to establish animal tumor models for studying tumorigenesis and development mechanisms.
| Storage | -20°C, stored under nitrogen |
| M.Wt | 117.11 |
| Cas No. | 759-73-9 |
| Formula | C3H7N3O2 |
| Synonyms | N-Nitroso-N-ethylurea; ENU; NSC 45403 |
| Solubility | ≥18.4 mg/mL in DMSO; insoluble in EtOH; ≥9.2 mg/mL in H2O |
| Chemical Name | 1-ethyl-1-nitrosourea |
| Canonical SMILES | O=NN(C(=O)N)CC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
