Signaling pathways
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BA8409 Fmoc-Ala-Glu-Asn-Lys-NH2Summary: Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase inhibitory peptide that inhibits APP cleavage of the amyloid precursor protein. - BA8411 TrontinemabSummary: Trontinemab is a bispecific humanized IgG1-κ antibody targeting amyloid βA4 precursor protein and transferrin receptor p90,CD71.
- BA8413 Aftin-4Summary: Inducer of beta-amyloid.
- BA8414 AZD4694Summary: AZD4694 (NAV4694) is a PET radioligand for neuroimaging of fluorinated beta-amyloid (Aβ) plaques.
- BA8415 PhenserineSummary: Phenserine ((-)-Eserolinephenylcarbamate), a derivative of Physostigmine, is a potent, non-competitive, long-acting and selective inhibitor.
- BA8416 HEPPSSummary: HEPPS (EPPS) is a buffer solution with an effective pH range of 7.3 to 8.7.
- BA8417 X-34Summary: X-34 is a lipophilic, bright yellow-green fluorescent derivative of Congo red (Congored).
- BA8419 BSBSummary: BSB is a Congo red-derived fluorescent probe.
- BA8420 TML-6Summary: TML-6 is an orally effective curcumin derivative that inhibits the synthesis of beta-amyloid precursor protein and beta-amyloid.
- BA8421 JNJ-40418677Summary: JNJ-40418677 is an orally active gamma-secretase modulator that crosses the blood-brain barrier.