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Biochemical Reagent
Signaling pathways

Signaling pathways

BA8441 BACE2-IN-1

Summary: BACE2-IN-1 is a highly selective inhibitor with an inhibition constant of 1.6 nM.
BA8442 Elenbecestat

Summary: Elenbecestat (E2609) is a highly potent, orally active, CNS permeable inhibitor.
BA8443 Umibecestat

Summary: Umibecestat (CNP520) is a β-site amyloid precursor protein cleavage enzyme-1 inhibitor with values of 11 nM and 10 nM in human BACE-1 and murine BACE-1, respectively.
BA8444 BACE1-IN-1

Summary: A potent and highly brain permeable inhibitor.
BA8445 Cassiaside

Summary: Cassiaside is a naphthyl ketone glycoside that exhibits a mixed type of inhibition (.
BA8446 PF-06751979

Summary: PF-06751979 is an effective.
BA8447 Aloenin

Summary: Aloenin (AloeninA) is a natural product with potent scavenging activity against peroxyl radicals and moderate inhibitory activity against β-secretase (IC50=14.95 μg/mL).
BA8448 CS587

Summary: CS587 is a specific inhibitor and is neurocytotoxic at 10 μM.
BA8449 TIM-063

Summary: TIM-063 is a selective and cell permeable inhibitor.
BA8450 CaMKIIα-IN-1

Summary: CaMKIIα-IN-1 is an orally active inhibitor of calcium/calmodulin-dependent protein kinase IIα.